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Protogracillin is an important class of natural products that exist in a variety of plants, especially medicinal plants. Dioscorea fibrillum is an active ingredient of C-27 steroidal glycosides.

Protogracillin has various physiological activities. Plants rich in such glycosides usually have certain effects on rheumatoid arthritis, atherosclerosis, hyperlipidemia, coronary heart disease, angina pectoris, cancer, diabetes, etc. therapeutic and preventive effects.

ChEBI: Protogracillin is a steroid saponin.

Protogracillin is a steroidal saponin isolated from Dioscorea zingiberensis Wright (DZW). Steroidal saponins from DZW rhizomes have antithrombotic effects and the potential to reduce the risk of cardiovascular disease.