ChemicalBook CAS DataBase List 544450-68-2

544450-68-2

Name	3-Thiophenecarboxylic acid, 2-[(4-chlorobenzoyl)amino]-4-ethyl-5-methyl-, methyl ester
CAS	544450-68-2
Molecular Formula	C16H16ClNO3S
MDL Number	MFCD03379002
Molecular Weight	337.82
MOL File	544450-68-2.mol

Chemical Properties

storage temp.	4°C, away from moisture and light
solubility	DMSO: 33.33 mg/mL (98.66 mM)
form	Solid
color	Off-white to light yellow

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Animal Model:	Male sP and Wistar rats.
Dosage:	0, 2.5, 5 and 10 mg/kg.
Administration:	Intraperitoneally (administered 30 min before the start of the self-administration, reinstatement, and locomotor activity sessions.).
Result:	The magnitude of the reducing effect of the compound on number of lever-responses for alcohol averaged approximately 30, 55, and 70%, in com parison to the vehicle-treated rat group, in the rat groups treated with 2.5, 5, and 10 mg/kg COR659, respectively. The magnitude of the reducing effect of COR659 on number of lever-responses for alcohol averaged approximately 20, 40, and 80%, in comparison to the vehicletreated rat group, in the rat groups treated with 2.5, 5, and 10 mg/kg COR659, respectively.

544450-68-2

Chemical Properties

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Biological Activity

in vitro

in vivo

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