54156-23-9

K118 is a water soluble inhibitor of SH2-containing inositol 5' phosphatase 1 (SHIP1). K118 reverses age- and diet-associated obesity and metabolic syndrome.

(3β,5α)-Androstan-3-amine (hydrochloride) is an active compound.

[1] First BRET‐based screening assay performed in budding yeast leads to the discovery of CDK5/p25 interaction inhibitors