Description
RA 642 is a PDE-inhibitor.
Uses
RA642 is a compound with vasodilatory and hypertensive effects, with the activity of increasing arterial blood pressure, enhancing cerebral blood flow, reducing cerebrovascular resistance and peripheral resistance, and having a papaverine-like relaxant effect on smooth muscle in anesthetized animals.
References
[1] High-performance liquid chromatographic assay for RA 642, a compound with cardiovascular effect, in human and rabbit serum alpha
[2] RA 642, a pyrimido-pyrimidine-derivative with vasodilating and hypertensive potency
