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Ethyl 4-((tert-Butoxycarbonyl)(methyl)amino)-3-oxobutanoate is an intermediate for the synthesis of 1-Methyl-4-imidazoleacetic Acid Hydrochloride (M323800), which is a metabolite of histamine (H436500), which is produced by mast cells and involved with the inflammatory response. 1-Methyl-4-imidazoleacetic Acid Hydrochloride can also be used to synthesize N-[1-(9,10-methano-9-anthracenylmethyl)-4-piperidinyl]alkanamides and analogs as dopamine D2 receptor antagonists.