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N-Methylnuciferine iodide, an alkaloid from Lotus Plumule, ameliorate lipopolysaccharide-induced depression-like behavior[1].

[1] Chen S, et al. Natural alkaloids from lotus plumule ameliorate lipopolysaccharide-induced depression-like behavior: integrating network pharmacology and molecular mechanism evaluation. Food Funct. 2019 Sep 1;10(9):6062-6073. DOI:10.1039/c9fo01092k