5218-08-6

BM 21.1298 inhibits HIV-1 reverse transcriptase.

BM 21.1298 is a selective and high specific nonnucleoside immunodeficiency virus type 1 reverse transcriptase (HIV-1 RT) inhibitor with antiviral activity[1].

[1] Maass G, et al. Viral resistance to the thiazolo-iso-indolinones, a new class of nonnucleoside inhibitors of human immunodeficiency virus type 1 reverse transcriptase. Antimicrob Agents Chemother. 1993 Dec;37(12):2612-7. DOI:10.1128/AAC.37.12.2612