52-26-6

Chemical Properties

Appearance	White or almost white, crystalline powder or colourless, silky needles or cubical masses, efflorescent in a dry atmosphere.
Melting point	about 200° (dec)
alpha	D25 -113.5° (c = 2.2 in H2O, anhydr basis)
storage temp.	−20°C
solubility	Soluble in water, slightly soluble in ethanol (96 per cent), practically insoluble in toluene.
form	Powder
Water Solubility	Soluble to 50 mM in water
Contact allergens	Morphine bitartrate caused contact dermatitis in a worker at a plant producing opium alkaloids. Morphine hydrochloride and morphine bitartrate showed patchtest- positive reactions in another patient with contact dermatitis working in the production of concentrated poppy straw. We observed a concomitant reaction between a morphine base and a codeine base in a patient with drug skin eruption due to codeine. less more
Uses	Opioid receptor agonist; analgesic. less more

Hazard Codes	F,T
Risk Statements	11-23/24/25-39/23/24/25 less more
Safety Statements	7-16-24-33-36/37-45 less more
RIDADR	UN 1230 3/PG 2
WGK Germany	1
Safety Profile	Poison by ingestion, intraperitoneal, intravenous, parenteral, and subcutaneous routes. An experimental teratogen. Experimental reproductive effects. Abuse leads to habituation or addiction. When heated to decomposition it emits very toxic fumes of NOx and HCl. less more
Toxicity	LD50 in mice (mg/kg): 226-318 i.v. (Buchwald, Eadie) less more