52-26-6

Name MORPHINIUM CHLORIDE
CAS 52-26-6
EINECS(EC#) 200-136-2
Molecular Formula C17H20ClNO3
MDL Number MFCD00133542
Molecular Weight 321.8
MOL File 52-26-6.mol
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Chemical Properties

Appearance White or almost white, crystalline powder or colourless, silky needles or cubical masses, efflorescent in a dry atmosphere.
Melting point  about 200° (dec)
alpha  D25 -113.5° (c = 2.2 in H2O, anhydr basis)
storage temp.  −20°C
solubility  Soluble in water, slightly soluble in ethanol (96 per cent), practically insoluble in toluene.
form  Powder
Water Solubility  Soluble to 50 mM in water
Contact allergens
Morphine bitartrate caused contact dermatitis in a worker at a plant producing opium alkaloids. Morphine hydrochloride and morphine bitartrate showed patchtest- positive reactions in another patient with contact dermatitis working in the production of concentrated poppy straw. We observed a concomitant reaction between a morphine base and a codeine base in a patient with drug skin eruption due to codeine.
Uses
Opioid receptor agonist; analgesic.

Safety Data

Hazard Codes  F,T
Risk Statements 
Safety Statements 
RIDADR  UN 1230 3/PG 2
WGK Germany  1
REACH Registrations Active
Safety Profile
Poison by ingestion, intraperitoneal, intravenous, parenteral, and subcutaneous routes. An experimental teratogen. Experimental reproductive effects. Abuse leads to habituation or addiction. When heated to decomposition it emits very toxic fumes of NOx and HCl.
Toxicity
LD50 in mice (mg/kg): 226-318 i.v. (Buchwald, Eadie)

Hazard Information

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