Uses
CNS stimulant; anorexic. More active isomer of Amphetamine. Induces release of catecholamines and serotonin by displacing the monoamines from their vesicular storage sites; blocks catecholamine reuptake.
Controlled substance (stimulant)
Definition
ChEBI: A 1-phenylpropan-2-amine that has S configuration.
Brand name
Dexampex (Teva); Dexedrine (GlaxoSmithKline); Dextrostat (Shire); Ferndex (Ferndale).
World Health Organization (WHO)
Schedule II of the 1971 Convention on Psychotropic Substances. See WHO
comment for amfetamine.
(Reference: (UNCPS2) United Nations Convention on Psychotropic Substances (II),
, , 1971)
Synthesis
The compound can be prepared by optical
resolution of amphetamineor directly
from (-)-norephedrine by conversion to
the (+)-chloroamine followed by catalytic hydrogenation .
