Description
A morphine type alkaloid, this base is a minor constituent of the seeds of
Papaver nudicaule var. amurense. It forms clusters of colourless crystals from
Me2CO and has [α] 22
D - 52° (c 1.0, CHCI3). The salts are crystalline and include
the hydriodide, m.p. 198°C (dec.); perchlorate, m.p. 188°C (dec.) and the
picrate, m.p. 150°C (dec.). The structure given above has been determined on the
basis of the infrared, NMR and mass spectra.
References
Boit, Flentje., Naturwiss., 47,180 (1960)
Flentje, Dopke, Jeffs., ibid, 52,259 (1965)
Dopke, Flentje, Jeffs., Tetrahedron, 24,4459 (1968)
Absolute configuration:
Barton et ai., Chern. Ber., 100,2457 (1967)
Circular dichroism:
Snatzke, Wollenberg.,!. Chern. Soc., C, 1581 (1966)
