444717-56-0

Name	(8R)-8-ETHYL-1,4,7,8-TETRAHYDRO-4-5H-IMIDAZO[2,1-I]PURIN-5-ONE
CAS	444717-56-0
Molecular Formula	C16H17N5O
MDL Number	MFCD06798317
Molecular Weight	295.34
MOL File	444717-56-0.mol

Synonyms

PSB 11 HYDROCHLORIDE (8R)-8-ETHYL-1,4,7,8-TETRAHYDRO-4-5H-IMIDAZO[2,1-I]PURIN-5-ONE (8R)-8-ETHYL-1,4,7,8-TETRAHYDRO-4-5H-IMIDAZO[2,1-I]PURIN-5-ONE HYDROCHLORIDE 5H-Imidazo[2,1-i]purin-5-one, 8-ethyl-3,4,7,8-tetrahydro-4-methyl-2-phenyl-, (8R)-

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Chemical Properties

storage temp.

Store at +4°C

Hazard Information

Uses

PSB 11 Hydrochloride is a potent and selective antagonist of Adenosine receptor A3-R.

Biological Activity

Potent and selective antagonist for the human adenosine A 3 receptor, with low affinity for the rat A 3 receptor (K i values are 2.3 and > 10000 nM respectively). Displays > 1000-fold selectivity over human A 1 and A 2A receptors (K i values are 4.1 and 3.3 μ M respectively) and > 180-fold selectivity over rat A 1 , rat A 2A and mouse A 2B receptors. Acts as an inverse agonist in the [ 35 S]GTP γ S binding assay in hA 3 -CHO cells (IC 50 = 36 nM).

Supplier

3B Pharmachem (Wuhan) International Co.,Ltd.

Telephone 18930552037

Websitehttps://www.chemicalbook.com/ShowSupplierProductsList13285/0_EN.htm

DAYANG CHEM (HANGZHOU) CO.,LTD

Telephone+86-88938639 +86-17705817739

Websitewww.dycnchem.com

Guangzhou Junuo Biotechnology Co., Ltd.

Telephone13432975901

Websitehttps://www.chemicalbook.com/ShowSupplierProductsList664287/0_EN.htm

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