Argyrin D
Cyclo[2,3-didehydroalanyl-N-methylglycyl-2-[(1R)-1-aminoethyl]-4-thiazolecarbonyl-L-tryptophyl-4-methoxy-2-methyl-L-tryptophylglycyl-(2R)-2-aminobutanoyl]
Argyrin D is a natural cyclic, non-ribosomal peptide that displays a promising antimicrobial activity against Pseudomonas aeruginosa[1].
References
[1] Wieland M, et al. The cyclic octapeptide antibiotic argyrin B inhibits translation by trapping EF-G on the ribosome during translocation. Proc Natl Acad Sci U S A. 2022 May 10;119(19):e2114214119. DOI:10.1073/pnas.2114214119
