426821-41-2

ChEBI: (Z)-3-(4-iodophenyl)-2-mercaptoacrylic acid is an organoiodine compound that is acrylic acid in which the vinylic hydrogens at positions 2 and 3 are replaced by mercapto and 4-iodophenyl groups respectively (the Z geoisomer). It has a role as a calpain inhibitor and an apoptosis inhibitor. It is an organoiodine compound, a member of cinnamic acids and a thioenol. It is functionally related to a trans-cinnamic acid.

Cell permeable: yes''Primary Target
Calpain-1''Product does not compete with ATP.''Reversible: no''Target Ki: 210 nM for calpain-1 and 370 nM for calpain-2

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