Description
Linoleoyl ethanolamide phosphate is an intermediate in the biosynthesis of linoleoyl ethanolamide that can be generated through phospholipase C-
mediated hydrolysis of N-
acylphosphatidylethanolamine.
1 Linoleoyl ethanolamide phosphate, along with other endogenous N-
acylethanolamines, is thought to play a role in the regulation of food intake by selective prolongation of feeding latency and post-
meal interval.
2
Uses
Linoleoyl ethanolamide phosphate is an intermediate in the biosynthesis of Linoleoyl ethanolamide (HY-113421). Linoleoyl ethanolamide phosphate combined with other endogenous N-acylethanolamines plays a role in the regulation of food intake by selective prolongation of feeding latency and post-meal interval[1][2].
References
1. Liu, J., Wang, L., Harvey-White, J., et al. Multiple pathways involved in the biosynthesis of anandamide Neuropharmacology 54(1),1-7(2008).
2. Hansen, H.S., and Diep, T.A. N-acylethanolamines, anandamide and food intake Biochem. Pharmacol. 78(6),553-560(2009).
