Uses
18:1 Phosphatidylbutanol or 1,2-dioleoyl-sn-glycero-3-phosphobutanol (sodium salt) has been used as a standard to measure phospholipase D (PLD) activity in smooth muscle cells (SMCs) and cancer cell lines by thin layer-chromatography.
Uses
18:1 Phosphatidylbutanol or 1,2-dioleoyl-
sn-glycero-3-phosphobutanol (sodium salt) may be used:
- to monitor the changes in phosphatidic acid (PA) dynamics in pollen tube after pharmacological treatments
- as an internal standard for extraction of phospholipids from whole blood
- as a standard to measure phospholipase D (PLD) activity in rat 2 fibroblasts by thin layer chromatograpghy (TLC)
General Description
Phosphatidylbutanol is a low polarity phosphatidylalcohol. This phospholipid is synthesized by the phospholipase D (PLD) catalyzed transphosphatidylation reaction of phosphatidylcholine (PC) and butanol.
Biochem/physiol Actions
Phosphatidylbutanol is used in phospholipase D activity assays as a potential biomarker.
