Uses
GSTP1-1 inhibitor 1 (compound 6b) is an irreversible, long-acting, glutathione S-transferase inhibitor with an IC50 of 21 μM targeting GSTP1-1 . GSTP1-1 is a key tumor suppressor target, and GSTP1-1 inhibitor 1 has potential anticancer activity[1].
References
[1] Shishido Y, et al. A Covalent Inhibitor for Glutathione S‐Transferase Pi (GSTP1‐1) in Human Cells[J]. ChemBioChem, 2019, 20(7): 900-905.