3808-42-2

Name	streptothricin F
CAS	3808-42-2
Molecular Formula	C19H34N8O8
MDL Number	MFCD01939650
Molecular Weight	502.526
MOL File	3808-42-2.mol

Synonyms

Yazumycin A BRN 6031385 Racemomycin A streptothricin F Streptothricin VI Antibiotic S-15-1A (3aS)-2-[[4-O-(Aminocarbonyl)-2-[[(S)-3,6-diamino-1-oxohexyl]amino]-2-deoxy-β-D-gulopyranosyl]amino]-1,3aβ,5,6,7,7aα-hexahydro-7β-hydroxy-4H-imidazo[4,5-c]pyridin-4-one 4H-Imidazo[4,5-c]pyridin-4-one, 2-[[4-O-(aminocarbonyl)-2-deoxy-2-[[(3S)-3,6-diamino-1-oxohexyl]amino]-β-D-gulopyranosyl]amino]-1,3a,5,6,7,7a-hexahydro-7-hydroxy-, (3aS,7R,7aS)-

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Chemical Properties

Boiling point	592.64°C (rough estimate)
density	1.3824 (rough estimate)
refractive index	1.6910 (estimate)
pka	12.66±0.70(Predicted)

Hazard Information

Uses

Streptothricin F is a bactericidal antibiotic. Streptothricin F interacts with the 30S subunit of 70S ribosome. Streptothricin F shows rapid, bactericidal activity against highly drug-resistant, carbapenem-resistant Enterobacterales (CRE) (MIC50 and MIC90: 2 and 4 μM, respectively) and Acinetobacter baumannii[1].

Definition

ChEBI: A streptothricin in which the peptide side-chain consists of a single unit of beta-lysine.

References

[1] Morgan CE, et al. Streptothricin F is a bactericidal antibiotic effective against highly drug-resistant gram-negative bacteria that interacts with the 30S subunit of the 70S ribosome. PLoS Biol. 2023 May 16;21(5):e3002091. DOI:10.1371/journal.pbio.3002091

Supplier

Zhejiang Huida Biotech Co., LTD

Telephone0571-89903022 18679456698

Websitehttps://www.huidacollection.cn

TargetMol Chemicals Inc.

Telephone4008200310 15002144251

Websitehttps://www.targetmol.cn/

Nantong QuanYi Biotechnology Co., Ltd

Telephone0513-66337626 18051384581

Websitehttps://www.chemhifuture.com/

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