3788-44-1

Tyrosylhistidine is a dipeptide consisting of tyrosine and histidine (Tyr-His). Tyrosylhistidine is an orally active antihypertensive peptide. Tyrosylhistidine reduces blood pressure in mice in a model of spontaneous hypertension[1].

ChEBI: Tyr-His is a dipeptide formed from L-tyrosine and L-histidine residues. It has a role as a metabolite. It is functionally related to a L-tyrosine and a L-histidine.

[1] Suetsuna K, et al. Antihypertensive effects of Undaria pinnatifida (wakame) peptide on blood pressure in spontaneously hypertensive rats. J Nutr Biochem. 2004 May;15(5):267-72. DOI:10.1016/j.jnutbio.2003.11.004