371213-22-8

VEGFR-2-IN-65 (Compound 07) is a VEGFR-2 inhibitor. VEGFR-2-IN-65 has H-bond interactions with Cys180. VEGFR-2-IN-65 inhibits tube formation in HUVECs[1].

VEGFR2

[1] Zhang L, et al. Discovery of novel vascular endothelial growth factor receptor 2 inhibitors: a virtual screening approach. Chem Biol Drug Des. 2012 Dec;80(6):893-901. DOI:10.1111/cbdd.12036