3705-26-8

White powder

Cyclo(L-Phe-L-Pro) is a diketopiperazine formed by the fusion of phenylalanine and proline, reported as a secondary metabolite of fungi and bacteria. In Pseudomonas aeruginosa, cyclo(L-Phe-L-Pro) is capable of activating N-acylhomoserine lactones (AHLs). Cyclo(L-Phe-L-Pro) is also capable of activating or antagonizing other LuxR-based quorum-sensing systems. While the mode of action of cyclo(L-Phe-L-Pro) is not known, its activity suggests the existence of cross talk among bacterial signalling systems.

Cyclo(L-prolyl-L-phenylalanyl) is a diketopiperazine derivative isolated from Bacillus thuringiensis and Bacillus endophyticus.

ChEBI: Cyclo(L-Phe-L-Pro) is an organic molecular entity. It has a role as a metabolite.