36507-31-0

Name	4-methylhistamine
CAS	36507-31-0
Molecular Formula	C6H11N3
MDL Number	MFCD01721795
Molecular Weight	125.17
MOL File	36507-31-0.mol

Synonyms

C025566 4-methylhistamine 5-Methylhistamine 4-Methylhistamine hydride 5-Methyl-1H-imidazole-4-ethanamine 5-(2-Aminoethyl)-4-methylimidazole 1H-Imidazole-5-ethanamine,4-methyl- 1H-Imidazole-4-ethanamine, 5-methyl- 2-(5-Methyl-1H-imidazol-4-yl)-ethylamine 2-(4-Methyl-1H-imidazol-5-yl)ethan-1-amine

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Hazard Information

Uses

4-Methylhistamine is a potent agonist of histamine 4 receptor (H4R). 4-Methylhistamine has the potential for the research of immune-related diseases such as cancer and autoimmune disorders[1][2].

Definition

ChEBI: An aralkylamino compound that is histamine bearing a methyl substituent at the 5 position on the ring.

References

[1] Ahmad SF, et al. Stimulation of the histamine 4 receptor with 4-methylhistamine modulates the effects of chronic stress on the Th1/Th2 cytokine balance. Immunobiology. 2015;220(3):341-349. DOI:10.1016/j.imbio.2014.10.014
[2] Kim CH, et al. Inhibitory Effect of Imiquimod-Induced Psoriasis-Like Skin Inflammation in Mice by Histamine H4 Receptor Agonist 4-Methylhistamine. Scand J Immunol. 2016 Jun;83(6):409-17. DOI:10.1111/sji.12420

Supplier

Shanghai Haohong Pharmaceutical Co., Ltd.

Telephone400-8210725 4008210725

Websitehttps://www.leyan.com/

TargetMol Chemicals Inc.

Telephone 4008200310

Websitehttps://www.targetmol.cn/

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