364052-84-6

ZINC04177596 is a novel Nef Protein Inhibitor; Anti-HIV.

ZINC04177596 is a potent HIV-negative factor (HIV-Nef) protein inhibitor. Nef is an accessory gene product of HIV and has an imperative role in viral replication and AIDS pathogenesis[1].

[1] Moonsamy S, et al. Identification of Binding Mode and Prospective Structural Features of Novel Nef Protein Inhibitors as Potential Anti-HIV Drugs. Cell Biochem Biophys. 2017;75(1):49-64. DOI:10.1007/s12013-016-0774-1