3627-62-1

crystallization. Melting point 53 ℃. Boiling point 148/544Pa (4mmHg).

1-methyl-4-phenylpiperidine-4-carbonitrile can be used as an intermediate in the synthesis of meperidine (Meluidine).

1-methyl-4-phenylpiperidine-4-carbonitrile is prepared by reacting by bis (β-chloroethyl) methylamine hydrochloride and benzyl cyanide condensation in the participation of sodium amide.