ChemicalBook CAS DataBase List 353495-21-3

353495-21-3

Name	3H-Cyclopenta[c]quinoline, 3a,4,5,9b-tetrahydro-8-nitro-4-phenyl-
CAS	353495-21-3
Molecular Formula	C18H16N2O2
Molecular Weight	292.33
MOL File	353495-21-3.mol

Chemical Properties

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Animal Model:	NSGS mice, K562 (ASXL1-WT/Y591^) xenograft model and patient-derived tumor cells (ASXL1-WT/Q588^) model^[1]
Dosage:	50 mg/kg/d
Administration:	Intraperitoneal injection, drug treatments were started at day 28 after transplantation
Result:	Significantly delayed progression of disease in both models.