34967-23-2

2,6-Dimethoxybenzylamine hydrochloride (Compound 5) exhibits reversible inhibitory activity against copper amine oxidase (CAO), that inhibits benzylamine oxidase (BAO) and monoamine oxidase B (MAO B) with IC50 of 120 μM and 190 μM[1].

[1] Lucchesini F, et al., Synthesis of 2,6-disubstituted benzylamine derivatives as reversible selective inhibitors of copper amine oxidases. Bioorg Med Chem. 2014 Mar 1;22(5):1558-67. DOI:10.1016/j.bmc.2014.01.037