34634-22-5

SF5 (2,2-Diphenylethyl isothiocyanate) is a sulforaphane analog. SF5 inhibits apoptosis by the JNK-p53-caspase pathway. SF5 can be used as a new renal protective agent for drug-resistant acute renal disease[1].

[1] Kim T, et al. The synthesis of sulforaphane analogues and their protection effect against cisplatin induced cytotoxicity in kidney cells. Bioorg Med Chem Lett. 2015 Jan 1;25(1):62-6. DOI:10.1016/j.bmcl.2014.11.014