343263-95-6

Name	DH 97
CAS	343263-95-6
Molecular Formula	C22H26N2O
MDL Number	MFCD02262121
Molecular Weight	334.45
MOL File	343263-95-6.mol

Synonyms

DH 97 N-PENTANOYL-2-BENZYLTRYPTAMINE N-[2-(2-benzyl-1H-indol-3-yl)ethyl]pentanamide 1-Pentanone,1-[3-(2-aminoethyl)-2-(phenylmethyl)-1H-indol-1-yl]-

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Chemical Properties

storage temp.	Store at RT
solubility	DMSO: soluble
form	A crystalline solid

Hazard Information

Description

DH 97 is an antagonist of melatonin receptor 2 (MT₂; K_is = 252 and 1,100 for human MT₂ and MT₁ receptors, respectively).

Definition

ChEBI: N-[2-[2-(phenylmethyl)-1H-indol-3-yl]ethyl]pentanamide is a member of indoles.

Biological Activity

A relatively potent MT 2 melatonin receptor antagonist (pK i value = 8.03), displaying 89- and 229-fold selectivity over MT 1 and GPR50 (melatonin-related orphan receptor) respectively.

Supplier

3B Pharmachem (Wuhan) International Co.,Ltd.

Telephone821-50328103-801 18930552037

Websitehttps://www.chemicalbook.com/ShowSupplierProductsList13285/0.htm

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Telephone 18818260767

Websitehttp://www.chemegen.com

Nantong QuanYi Biotechnology Co., Ltd

Telephone0513-66337626 18051384581

Websitehttps://www.chemhifuture.com/

Shanghai Yifei Biotechnology Co. , Ltd.

Telephone021-65675885 18964387627

Websitehttp://www.efebio.com

TargetMol Chemicals Inc.

Telephone 15002134094

Websitehttps://www.targetmol.cn/

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