Description
UK-414,495 acts as a potent, selective inhibitor of the enzyme neutral endopeptidase, which normally serves to break down the neuropeptide VIP. UK-414,495 is a drug used for the treatment of female sexual arousal disorder.
Uses
(Rac)-UK-414495 (example 7) is a potent neutral endopeptidase (NEP) inhibitor. (Rac)-UK-414495 causes potentiation of cAMP in the sexual genitalia of the female[1].
References
[1] Graham NM, et, al. NEP inhibitors for the treatment of female sexual dysfunction. EP1481667A1.
