A-420983 is a potent, orally active inhibitor of Lck and can be used in studies involving animal models of delayed-type hypersensitivity and organ transplant rejection[1].
References
[1] Borhani DW, et al. A-420983: a potent, orally active inhibitor of lck with efficacy in a model of transplant rejection. Bioorg Med Chem Lett. 2004;14(10):2613-2616. DOI:10.1016/j.bmcl.2004.02.101
