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CAS DataBase List
305820-76-2
305820-76-2
Name
PD 173956
CAS
305820-76-2
Molecular Formula
C20H13Cl2FN4O
Molecular Weight
415.25
MOL File
305820-76-2.mol
Synonyms
PD 173956
6-(2,6-dichlorophenyl)-2-(4-fluoroanilino)-8-methylpyrido[2,3-d]pyrimidin-7-one
Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-(2,6-dichlorophenyl)-2-[(4-fluorophenyl)amino]-8-methyl-
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Chemical Properties
Boiling point
584.9±60.0 °C(Predicted)
density
1.483±0.06 g/cm3(Predicted)
pka
3.01±0.20(Predicted)
Hazard Information
Uses
PD173956 is a pyridopyrimidine Bcr-Abl kinase inhibitor with high selectivity for the P-loop mutant form of Bcr-Abl[1].
References
[1] Inhibition of Wild-Type and Mutant Bcr-Abl by Pyrido-Pyrimidine-Type Small Molecule Kinase Inhibitors
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TargetMol Chemicals Inc.
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15002134094
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https://www.targetmol.cn/
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