KHK-IN-5 (Compound 18) is a KHK inhibitor. KHK-IN-5 can be used for the research of nonalcoholic fatty liver disease (NAFLD), nonalcoholic steatohepatitis (NASH), and type 2 diabetes (T2DM)[1].
References
[1] Sabnis RW. Novel Cyanopyridine Compounds as KHK Inhibitors for Treating NAFLD, NASH, and Type II Diabetes. ACS Med Chem Lett. 2024 Jul 23;15(8):1191-1192. DOI:10.1021/acsmedchemlett.4c00332