3023114-93-1

Antibacterial agent 172 (Compound 6a) is a <,i>Clostridioides difficile (Cd) SpoVD inhibitor (IC50=89 nM) that effectively inhibits sporulation of Clostridioides difficile. Antibacterial agent 172 can be used in the study of bacterial infections[1].

[1] Cun WY, et al. Design, Synthesis, and Evaluation of Cephamycin-Based Antisporulation Agents targeting Clostridioides difficile. J Med Chem. 2024 Jan 11;67(1):450-466. DOI:10.1021/acs.jmedchem.3c01662