PLpro-IN-5 (compound 21) is a PLPro protease inhibitor with an IC50 value of 91.14 nM. PLpro-IN-5 shows broad-spectrum antivirus, especially for SARS-CoV, MERS-CoV, SARS-CoV-2[1].
References
[1] WeiHe, et al. PLpro protein inhibitor and preparation method and application thereof. CN116969941A.
