CYP51-IN-19 (compound C07) is a potent CYP51 inhibitor. CYP51-IN-19 stimulates reactive oxygen species (ROS) and exhibits potent fungicidal activity[1].
References
[1] Yan Z, et al. Discovery of Novel α,β-Unsaturated Amide Derivatives as Candidate Antifungals to Overcome Fungal Resistance. J Med Chem. 2024 Aug 8;67(15):12601-12617. DOI:10.1021/acs.jmedchem.4c00593
