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The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3)-P₁ (1,2-dioctanoyl) is a synthetic analog of natural PtdIns featuring C8:0 fatty acids at the sn-1 and sn-2 positions. The compound features the same inositol and DAG stereochemistry as the natural compound. PtdIns-(3)-P₁ can be phosphorylated to di- (PtdIns-P₂; PIP₂) and triphosphates (PtdIns-P₃; PIP₃) by phosphatidyl inositol (PI)-specific kinases.

08:0 PI(3)P has been used in the preparation of model membrane for protein reconstitution and structural studies.

Glycerophospholipids act as regulators of various enzyme activities, and can be used as biological markers to indicate pathological states.

Phosphatidylinositol 3-monophosphate (PI3P) is a lipid, found abundantly in eukaryotic cells. It is also present at low level in mammalian cells.

Phosphatidylinositol 3-monophosphate (PI3P) participates in vesicular trafficking processes. It also plays a key role in endocytosis.