h-NTPDase-IN-5 (compound 3b) is a pan-inhibitor of NTPDase with IC50s of 1.10 μM (h-NTPDase1), 44.73 μM (h-NTPDase2), 26.14 μM (h-NTPDase3), 0.32 μM (h- NTPDase8).
References
[1] Zaman G, Ullah S, Uzair M, et al. Synthesis of Thieno [3, 2‐d] pyrimidine Derivatives through Sequential SNAr and Suzuki Reactions as Selective h‐NTPDases Inhibitors[J]. ChemMedChem, 2023: e202300165.
