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ChemicalBook CAS DataBase List 2924092-72-6

2924092-72-6 Structure

2924092-72-6

Name	3-(4-Bromo-2-chloro-5-fluorophenyl)piperidine-2,6-dione
CAS	2924092-72-6

Synonyms

CRBN ligand-110 3-(4-Bromo-2-chloro-5-fluorophenyl)piperidine-2,6-dione

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Hazard Information

Uses

CRBN ligand-110 is a CRBN-type E3 ubiquitin ligase ligand that can be used to prepare PROTAC.

IC 50

Cereblon

References

[1] Mileti? N, et al. Workflow for E3 Ligase Ligand Validation for PROTAC Development. ACS Chem Biol. 2025 Feb 21;20(2):507-521. DOI:10.1021/acschembio.4c00812

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