PAV-104 inhibits SARS-CoV-2 replication, with the MOI of 0.01. PAV-104 can interact with SARS-CoV-2 nucleocapsid (N) and interfered with its oligomerization, blocking particle assembly[1].
References
[1] Satish Pillai, et al. A viral assembly inhibitor blocks SARS-CoV-2 replication in airway epithelial cells. Res Sq [Preprint]. 2023 May 17:rs.3.rs-2887435. DOI:10.21203/rs.3.rs-2887435/v1
