iNOS inhibitor-10 is an iNOS inhibitor (IC50: 65 nM). iNOS inhibitor-10 has antiproliferative effect against triple negative breast cancer cells[1].
IC 50
iNOS: 0.065 μM (IC50); eNOS: >50 μM (IC50)
References
[1] Carrión MD, et al. New amidine-benzenesulfonamides as iNOS inhibitors for the therapy of the triple negative breast cancer. Eur J Med Chem. 2023 Feb 15;248:115112. DOI:10.1016/j.ejmech.2023.115112
