Uses
It is a natural product derived from plant source th at finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.
Biological Activity
According to the existing researchColadin exhibited notable anti-cancer properties by substantially reducing cell proliferation and mitochondrial dehydrogenase activity in mouse B16F1 melanoma cells. These effects induced apoptosis through mechanisms involving decreased mitochondrial membrane potential and mitochondrial respiratory rateunderscoring its potential as a natural anti-cancer agent. Isolated from the roots of Ferulago campestriscoladinalong with other compounds such as umbelliprenin and epielmanticinedisplayed inhibitory activity against Acetylcholinesterase (AChE) with an IC50 of 0.1 mMsuggesting its potential application in the treatment of neurological disorders like Alzheimerμs disease. Coladinidentified as one of the constituents in Heptaptera triquetra fruitexhibited remarkable inhibitory activity against acetylcholinesterase (AChE)human carbonic anhydrase isoenzyme (h
