2804269-05-2

rac-N-desmethyl Ivabradine-d6 is intended for use as an internal standard for the quantification of N-desmethyl ivabradine (Item No. 27808) by GC- or LC-MS. N-desmethyl Ivabradine is an active metabolite of ivabradine (Item No. 15868).1 Ivabradine is metabolized by the cytochrome P450 (CYP) isoform CYP3A4.WARNING This product is not for human or veterinary use.

[1] GIAN MARCO ROSA. An evaluation of the pharmacokinetics and pharmacodynamics of ivabradine for the treatment of heart failure.[J]. Expert Opinion on Drug Metabolism & Toxicology, 2014, 10 2: 279-291. DOI: 10.1517/17425255.2014.876005