2803505-78-2

ENPP3 inhibitor 4g is an inhibitor of ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (ENPP1) and ENPP3 (IC₅₀s = 0.45 and 0.19 μM, respectively).¹

Enpp-1-IN-21 (compound 4g) is an inhibitor of ecto-nucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1), with IC50 values for ENPP1 and ENPP3 at 0.45 and 0.19 μM, respectively[1].

1. Ullah, S., Pelletier, J., Sévigny, J., et al. Synthesis and biological evaluation of arylamide sulphonate derivatives as ectonucleotide pyrophosphatase/phosphodiesterase-1 and -3 inhibitors ACS Omega 7(30),26905-26918(2022).