HIV-1 inhibitor-71 (compound 2a) blocks the transport of endocytosed HIV-1 particles into nuclear envelope invagination (NEIs) that can inhibit productive infection[1].
References
[1] Daniela Carbone, et al. Triazole derivatives inhibit the VOR complex-mediated nuclear transport of extracellular particles: Potential application in cancer and HIV-1 infection. Bioorg Chem. 2024 Sep:150:107589. DOI:10.1016/j.bioorg.2024.107589