2748304-49-4

Mescaline (Item No. 11950) is a psychedelic phenethylamine that activates serotonin receptors, with preference for 5-HT2A over 5-HT2C (EC50 = 4 and 24 μM, respectively).1 Mescaline NBOMe is a derivative of mescaline having an N-(2-methoxybenzyl) addition at the amine. This addition on related phenethylamines increases the affinity and selectivity for the 5-HT2A receptor over other serotonin receptors.2 The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research applications.WARNING This product is not for human or veterinary use.

[1] AARON P. MONTE. Dihydrobenzofuran Analogues of Hallucinogens. 4. 1 Mescaline Derivatives 2[J]. Journal of Medicinal Chemistry, 1997, 40 19: 2997-3008. DOI: 10.1021/jm970219x
[2] MICHAEL R BRADEN. Molecular interaction of serotonin 5-HT2A receptor residues Phe339(6.51) and Phe340(6.52) with superpotent N-benzyl phenethylamine agonists.[J]. Molecular Pharmacology, 2006, 70 6: 1956-1964. DOI: 10.1124/mol.106.028720