Picroliv is a hepatoprotective mixture of compounds that is isolated from an herb native to the Himalayas.
1 Picroside I is an iridoid glycoside found in picroliv.
1 By itself, picroside I blocks changes in acid phosphatase activity, phospholipid levels, and lipid peroxide production induced by D-galactosamine in rat liver.
2 Picroside I also enhances neurite outgrowth in PC12D cells induced by basic fibroblast growth factor and 7S nerve growth factor when given at 60 μM.
3,4 At concentrations as low as 5 μM, picroside I enhances the ATPase activity of the efflux transporter P-glycoprotein.
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