Description
Methylone is a β-ketone analog of 3,4-methylenedioxymethamphetamine (3,4-MDMA; ） that has been detected in products marketed as bath salts, plant food, and tablets.
1,2 Similar to 3,4-MDMA, it acts on components of the monoaminergic systems.
3,4,5 5-methoxy Methylone is a cathinone derivative that bears a methoxy group similar to various tryptamine analogs including 5-methoxy MiPT , which are known to potently inhibit monoamine transport function.
5 The pharmacological and toxicological properties of this compound are not known. This product is intended for forensic and research purposes.
References
1. Kikura-Hanajiri, R., Uchiyama, N., and Goda, Y. Survey of current trends in the abuse of psychotropic substances and plants in Japan Leg. Med. (Tokyo) 13(3),109-115(2011).
2. Bossong, M.G., Van Dijk, J.P., and Niesink, R.J. Methylone and mCPP, two new drugs of abuse? Addict. Biol. 10(4),321-323(2005).
3. Cozzi, N.V., Sievert, M.K., Shulgin, A.T., et al. Inhibition of plasma membrane monoamine transporters by β-ketoamphetamines Eur. J. Pharmacol. 381(1),63-69(1999).
4. Nagai, F., Nonaka, R., and Satoh Hisashi Kamimura, K. The effects of non-medically used psychoactive drugs on monoamine neurotransmission in rat brain Eur. J. Pharmacol. 559(2-3),132-137(2007).
5. Sogawa, C., Sogawa, N., Ohyama, K., et al. Methylone and monoamine transporters: Correlation with toxicity Curr. Neuropharmacol. 9(1),58-62(2011).
