2684212-54-0

Psilocin-d6 (Item No. 34780) is an analytical reference standard intended for use as an internal standard for the quantification of psilocin (Item Nos. 9003135 | 11864 | 36971) by GC- or LC-MS. Psilocin is categorized as a tryptamine.1 Psilocin is the active metabolite of the psychedelic compound psilocybin (Item Nos. 9003134 | 14041) and the synthetic tryptamine 4-acetoxy DMT (psilacetin; Item Nos. 14056 | 35188).2,3 It induces the head-twitch response (HTR) in mice, indicating hallucinogenic potential.4 Psilocin is regulated as a Schedule I compound in the United States. This product is intended for research and forensic applications.WARNING This product is not for human or veterinary use.

[1] JOSEPH B. BLAIR. Effect of Ring Fluorination on the Pharmacology of Hallucinogenic Tryptamines[J]. Journal of Medicinal Chemistry, 2000, 43 24: 4701-4710. DOI: 10.1021/jm000339w
[2] ADAM L HALBERSTADT. Differential contributions of serotonin receptors to the behavioral effects of indoleamine hallucinogens in mice.[J]. Journal of Psychopharmacology, 2011, 25 11: 1548-1561. DOI: 10.1177/0269881110388326
[3] HADENA. GEIGER  R. N D  Madeline G Wurst. DARK Classics in Chemical Neuroscience: Psilocybin[J]. ACS Chemical Neuroscience, 2018, 9 10: 2438-2447. DOI: 10.1021/acschemneuro.8b00186
[4] GRANT C. GLATFELTER*, MICHAEL H. BAUMANN   Structure–Activity Relationships for Psilocybin, Baeocystin, Aeruginascin, and Related Analogues to Produce Pharmacological Effects in Mice[J]. ACS Pharmacology and Translational Science, 2022, 5 11: 1181-1196. DOI: 10.1021/acsptsci.2c00177