2649467-91-2

Suzetrigine phenol is the phenolate form of the sodium channel modulator Suzetrigine (HY-148800). Suzetrigine (VX-548) is an orally active and highly selective inhibitor of NaV1.8[1][2].

[1] Scarnati MS, et al. Using human stem cells as a model system to understand the neural mechanisms of alcohol use disorders: Current status and outlook. Alcohol. 2019 Feb;74:83-93. DOI:10.1016/j.alcohol.2018.03.008
[2] Preparation of substituted tetrahydrofuran amides as modulators of sodium channels. World Intellectual Property Organization, WO2021113627 A1 2021-06-10.