Mc-Leu-Gly-Arg is a cleavable ether linker for antibody-drug conjugates (ADC) design.
IC 50
Cleavable Linker
References
[1] Zhang D, et al. Immolation of p-Aminobenzyl Ether Linker and Payload Potency and Stability Determine the Cell-Killing Activity of Antibody-Drug Conjugates with Phenol-Containing Payloads. Bioconjug Chem. 2018 Feb 21;29(2):267-274. DOI:10.1021/acs.bioconjchem.7b00576
