2636798-38-2

WUN-98382 is a functionalized cereblon ligand for PROTAC? research and development. It incorporates an E3 ligase ligand plus an alkylC8 linker with a terminal amine ready for conjugation to a target protein ligand. WUN-98382 is Part of a range of functionalized tool molecules for PROTAC R&D. This product has no formal name.

Thalidomide-4-O-C8-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].

Cereblon

Store at -20°C

[1] Sato T, et al. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine.?Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11. DOI:10.3389/fcell.2021.629326
[2] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. DOI:10.7554/eLife.57277